Sanitization Products

Sanitization vs Sterilization:

 

Sterilization:

All microorganisms are killed or inactivated directly. This process uses extremely high or low temperatures, chemicals, gases, or radiation to destroy microbes. Effective against bacteria, viruses, and fungi.

Suitable for re-usable medical equipment and laboratory supplies. Typical solutions include autoclaves, ultrasonic baths, ethylene oxide, and/or irradiation chambers. At this time, we do not offer sterilization equipment.

Sanitization:

The reduction of microorganism levels until they are no longer harmful. For example, hand sanitizers that kill 99.99% of bacteria are a form of sanitization. Note that sanitization is much gentler than sterilization. Some products do not affect viruses, fungi, or fungal spores. It is important to select your sanitization agent carefully to meet the bactericidal/ fungicidal/ virucidal characteristics desired for your application.

 

The efficacy of a sanitization method is heavily impacted by the proper use of that agent. Typically, surfaces must be cleaned of any biofilms, grime, or thick layers prior to cleaning. These wet wipes are a good option. Various chemical sanitization agents may then be used. Common agents include alcohols, calcium hypochlorite, sodium hypochlorite, and quaternary ammonium compounds. Typically, there is then a required wait time of minutes to hours before the microbes are killed. If the surface is not wet with sanitizing agent during that whole time, the process will be less effective.

For a through review of the pros/cons of common sanitizing agents, please see the updated CDC guidelines. Agents reviewed include Alcohols, Chlorine Compounds, Formadehyde, Iodophors, Peracetic Acids, Phenols, and Quaternary Ammonium Compounds. If you have further questions about which agents best suit your particular use, feel free to contact us for help!

Alcohol sanitizers: Facts and Myths

Pros:
Safe on skin.

  • Broad efficacy and low cost.

Ethyl alcohol: Bacteria + Herpes Virus, Influenza, Adenovirus, Enterovirus, Rhinovirus, HIV, astrovirus, echovirus. Hepatitis B. Also effective against some fungi, including Blastomyces, Cryptococcus, Coccidioides, and Histoplasma.

Isopropyl alcohol: Bacteria + Herpes Virus, Influenza Virus, Hepatitis B.

Cons:

  • Lack action against spores. Cannot penetrate protein rich materials.

  • Evaporate quickly – the extended exposure time needed to kill some microbes is difficult to achieve unless the item is immersed in alcohol solution.

  • Damage certain materials after repeated use.

  • Flammable

The Details:

Alcohol sanitizers are usually one of two water-soluble chemical compounds—ethyl alcohol or isopropyl alcohol mixed with water.  Both of these alcohols are rapidly bactericidal (kill bacteria). They also are tuberculocidal, and have some fungicidal and virucidal activity but do not destroy bacterial spores.

For both isopropyl and ethyl alcohol, their activity drops sharply when diluted below 50% concentration, and the optimum bactericidal concentration is 60%–90% alcohol solutions in water.

Please note that a higher alcohol percentage is not always better. The way alcohols work is by denaturing pathogen proteins.This process is enhanced by the presence of water. At very high concentrations of alcohol, there is not enough water for the proteins to denature and the pathogens are simply preserved. It bears repeating that in most situations, a 60% - 90% solution of alcohol is ideal.

Ethyl alcohol, at concentrations of 60%–80%, is a potent virucidal agent inactivating all of the lipophilic viruses (e.g., herpes, vaccinia, and influenza virus) and many hydrophilic viruses (e.g., adenovirus, enterovirus, rhinovirus, and rotaviruses but not hepatitis A virus (HAV) or poliovirus). Ethyl alcohol can also inactivate human immunodeficiency virus (HIV), rotavirus, echovirus, and astrovirus. Ethyl alcohol (70%) was found to be the most effective concentration for killing the tissue phase of various fungi, specifically Cryptococcus neoformans, Blastomyces dermatitidis, Coccidioides immitis, and Histoplasma capsulatum.

 

Isopropyl alcohol is not active against the nonlipid enteroviruses but is fully active against the lipid viruses. Studies also have demonstrated the ability of ethyl and isopropyl alcohol to inactivate the hepatitis B virus(HBV) and the herpes virus.

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Chlorine compounds:

          The most prevalent chlorine products in the United States are solutions of 5.25%–6.15% sodium hypochlorite, usually called household bleach. They have a broad spectrum of antimicrobial activity, are commonly available, and are inexpensive and fast acting.

 

Pros:

  • Broad activity - these compounds are bactericidal, fungicidal, sporicidal, tuberculocidal, and virucidal.

  • They are relatively inexpensive, available in many forms, and leave non toxic residues.

Cons:

  • Commonly they are irritants.

  • Corrosive and damaging to fabrics

  • Works poorly in acidic environments.

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Quarternay Ammonium Compounds:

          Some of the chemical names of quaternary ammonium compounds used in healthcare are alkyl dimethyl benzyl ammonium chloride, alkyl didecyl dimethyl ammonium chloride, and dialkyl dimethyl ammonium chloride. The newer quaternary ammonium compounds (i.e., fourth generation), referred to as twin-chain or dialkyl quaternaries. They are typically fungicidal and bactericidal. Limited activity against viruses, though they do destroy some enveloped/lipophic strains. They are not sporicidal or tuberculocidal. They are most suitiable as general agents for cleaning floors, railings, and some surfaces. They are safe for skin contact.

 

Pros:

 

  • EPA-registered quaternary ammonium compounds are appropriate to use for disinfecting medical equipment that contacts intact skin.

  • Fungicidal (some)

  • Bactericidal (some)

 

Cons:

  • Gram-negative bacteria can survive or grow in them

  • Limited activity against non-enveloped viruses

  • They are not sporicidal or tuberculocidal.

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Opti-Cide

  • Medical Grade Wipes, 160ct.

  • Wide Spectrum, combines multiple active ingredients. Bactericidal,Fungicidal, Virucidal.

  • Very fast, cleans surface of most pathogens in 1 minute.

  • Safe on many surface types.  Non staining, no odor.

  • Available as Wipe, Spray, and liquid refill.

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Sani Cloth Prime

  • Medical grade wipes, 160ct

  • Available as single can or 12 can case.

  • Very broad antibacterial, anti-viral and anti-fungal properties.

  • Combines the power of Quaternary amines with alcohols to increase potency and spectrum.

  • Very fast, works in 1 minute or less.

  • Safe on most surfaces, non staining, no odor.

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Clorox Disinfectant

  • Chloride based cleaning agent

  • Broad activity against bacteria, common viruses, and fungi.

  • 225 single use wipes

  • Available as liquid and spray

  • Safe on most surfaces

  • Non toxic residue

  • Less effective in acidic conditions.

Our Recommendations:

Sani Cloth disinfectant

Sani Cloth

  • Medical Grade Wipes, 160ct.

  • Wide Spectrum, combines multiple active ingredients. Bactericidal,Fungicidal, Virucidal.

  • Kills 100+ organisms.

  • Works in minutes

  • Safe on many surface types.  Non staining, no odor.

  • Available as single (160 wipes) or 12 units (160 x 12).

Cavi Wipes disinfectant

Cavi-Wipes

  • Medical Grade Wipes, 160ct.

  • Wide Spectrum, combines multiple active ingredients. Bactericidal,Fungicidal, Virucidal.

  • In less than 3 minutes, kills HIV, MRSA, Hep B/C, Flu A, Pseudomonas, VRE, and more.

  • Safe on many surface types.  Non staining, no odor.  

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95% Ethyl Alcohol

  • Superior Virucidal activity to Isopropyl Alcohol. Inactivates HIV, influenza, and many other strains.

  • Broad antibacterial and anti fungal properties

  • Concentrated solution allows for self dilution as needed

  • Safe

 

  • Flammable

  • Limited activity vs. spores.

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